Effect of repeated stress on novelty-induced antinociception in rats

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چکیده

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Effect of repeated stress on novelty-induced antinociception in rats.

There is extensive evidence that acute stress induces an analgesic response in rats. On the other hand, repeatedly stressed animals may present the opposite effect, i.e., hyperalgesia. Furthermore, exposure to novelty is known to induce antinociception. The effects of repeated restraint stress on nociception after exposure to novelty, as measured by the tail-flick latency (TFL), were studied in...

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ژورنال

عنوان ژورنال: Brazilian Journal of Medical and Biological Research

سال: 2001

ISSN: 0100-879X

DOI: 10.1590/s0100-879x2001000200012